1) Yes, USB2, Firewire 400 and Firewire 800 interfaces are all included

2) All cables included.

3) The drive came formatted as FAT32. I formatted the drive as a Mac Extended drive and it allows files > 4GB

4) There is software on the hard disk itself and on supplied CD. For the mac there are two installs, a driver to support firewire and also backup software. The driver allows for intelligent update of the light on the front of the drive to show how much is stored. I’m afraid I’ve not tried the backup software and instead used Super Duper.